2nd generation antipsychotics reduce insulin sensitivity and cause weight gain in young people

Second generation antipsychotics are associated with clinically evident metabolic effects in young people after only 12 weeks, say US researchers (JAMA Psychiatry June 13, 2018. doi:10.1001/jamapsychiatry.2018.1088).
The study involved 144 young people aged 6 – 18 (mean 11) who were considered for treatment with an antipsychotic …

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Diabetes and pancreatic cancer

‘Recent-onset diabetes is a manifestation of pancreatic cancer and long-standing diabetes is a risk factor for this malignancy’, say US investigators (Journal of the National Cancer Institute, djy090, https://doi.org/10.1093/jnci/djy090).
Their cohort study included 49,000 people of African American or Latin ethnic origin who did not have …

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Too much and too little sleep linked with metabolic syndrome

The Health Examinees (HEXA) Study is a cohort study in South Korea designed to investigate the epidemiological, genetic and environmental factors that are associated with major chronic diseases in the population (Asian Pac J Cancer Prev 2015;16:1591-7).
A recent analysis of 133,600 participants enrolled between 2004 …

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UK children consume a year’s worth of sugar in 6 months

This eye-catching headline comes from Public Health England’s (PHE) publicity for its Change4Life campaign (www.nhs.uk/change4life). PHE says UK children aged 4 – 10 consume sugar equivalent to an average of 13 cubes per day compared with a recommended limit of 5 – 6. Intake is …

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Post-breast cancer hormone therapy may increase diabetes risk

Women with breast cancer who receive hormone therapy may face a 4-fold increase in the risk of developing diabetes, say Israeli researchers (J Clin Oncol 2018; April 28. DOI: 10.1200/JCO.2017.76.3524 Journal of Clinical Oncology).
Their case cohort study analysed outcomes for 2,246 women diagnosed with primary …

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Statins diabetes risk advice

“Patients should be reassured that the benefits of statins in preventing CVD events far outweigh the potential risk from elevation in plasma glucose, especially in individuals with increased HbA1c,‘’ according to a panel of European specialists (European Heart Journal, ehy182, https://doi.org/10.1093/eurheartj/ehy182).
Reviewing the evidence behind common …

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Millions pledged for diabetes research

Diabetes UK has announced grants totalling £2.6 million to fund research projects and PhD studentships. The projects supported will include a study to determine whether a combination of antibacterial agents found in a medieval treatment is effective in the management of infected foot ulcer and …

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Novel approach for diabetic kidney disease

A new class of anti-inflammatory drugs could offer a promising treatment for diabetic kidney disease (DKD) if the results of a Phase II trial are supported in larger studies.
US investigators assessed the efficacy of the oral JAK1/JAK2 inhibitor baricitinib in 129 people with type 2 …

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UK diabetes prevalence doubles in 20 years

The number of people in the UK known to have diabetes has now reached 3.7 million, with a further one million cases suspected but undiagnosed and 12.3 million at risk of developing diabetes, according to Diabetes UK (www.diabetes.org.uk). It also reported that over 100,000 people …

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Good start for Healthier You

Healthier You, the NHS diabetes prevention programme (https://preventing-diabetes.co.uk) is reaching its target audience and early uptake has been higher than expected, says Public Health England (Diabetic Medicine 28 December 2017. DOI: 10.1111/dme.13562).
Its analysis of 43,603 referrals between June 2016 and March 2017 showed that 49% …

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